TOBIAS GLEICHMANN
last modification: 2016-10-14
today:2025-01-07
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DNA electrophoresis:
Pre-amplified DNA is separated and visualized on a self-casted agarose gel.
Protein crystals of insulin:
Insulin is a essential hormone of our metabolism.
Crystallized thaumatin:
Thaumatin is a natural sweetener. It's up to 3000 times sweeter than sugar.
X-ray diffraction pattern of protein crystals:
Diffraction of highly brilliant synchrotron radiation on protein crystals is used to solve the 3D-structures of former crystallized proteins.
Nanoscale droplet arrays on glas:
Droplet-based protein or DNA arrays help to get insights into expression levels of a certain tissue sample.
Volume gradient array on transparent polymers:
Modern technology allows precise structering of liquids down to the low pl-range.
Raster electron microscopy of
Aspergillus niger
:
A. niger
is a well known, black mold fungus producing a couple of mycotoxines.
Close up raster electron image of
A. niger
:
A single sporangia of a
A. niger
sample is magnified by more detailed scanning.
Protein electron density map during structure determination:
Atomic structures of proteins are solved from X-ray diffraction data obtained from protein crystals.
Random mutagenesis for functional analysis of a protein:
A DNA sequence or gene encoding a protein of interest is modified by a error prone PCR protocol. Effects of certain mutations analysed by sequencing is coupled to the expression of another, fluorescent protein.
Raster electron microscopy of
Penecillium chrysogenum
:
Everybody knows penecillin,the first antibiotic extracted from
P. chrysogenum
by A. Flemming.
Light microscopy of
Lactobacillus brevis
:
L. brevis
is a none pathogen lactic acid bacteria of 2-9 µm in length.
Liht microscopy of
Saccharomyces cerevisiae
:
The beer & bread yeast.
S. cerevisiae
is probably the most and longest used microorganism in biotechnology production.
Protein crystalliaztion in a micro-droplet:
Precise handling of tiny volumes allowes for the development of new applications and massively scale-up.